Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | 64-18-6 | MFCD00003297 | 1L
Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | Purity: 98.0-100% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1L
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 25g | 480143861
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | C26H25N5O4S | 10MG
Ro 31-8220 formic is a small-molecule research reagent that acts as a potent, cell-permeable inhibitor of protein kinase C (PKC) and several other kinases. It is used in biochemical and cellular studies to probe PKC-dependent signaling, kinase selectivity, and downstream pathway effects such as JNK activation and c-Jun induction.
- Potent PKC inhibition with low-nanomolar IC50s.
- Inhibits multiple kinases for broad pathway interrogation.
- Cell-permeable for use in cellular assays.
- High purity solid with characteristic orange to red color.
- Stable when stored sealed at -20°C; in solvent can be stored at -80°C for extended periods.
- Available in small milligram pack sizes suitable for research use.
U.S. Pharmacopeia PROIONIC ACID 1.5ML AMPULES
Propionic Acid (1.5 mL/ampule; 3 ampules)U S PHARMACOPEIA mfg# 1572208
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 10 MM * 1 ML
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and available in various forms, including solid and as a 10 mM * 1 mL solution in DMSO.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Intended for research use only
- Purity of 99.91%
- Molecular weight of 403.56
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL (247.79 mM)
- Induces a dose-dependent decrease in circulating lymphocytes in vivo
- Achieves a maximum concentration of 4 μM in rats at 2 hours post-dose with a half-life of 8 hours
- Related to respiratory, inflammatory, and pulmonary diseases, and lung fibrosis
- Affects inflammation/immunology, GPCR/G protein, and LPL receptor signaling pathways
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 1 L
Linear Formula: HCOOH, Molecular Weight: 46.03, reagent grade, ≥95%.
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 1 L
Formic acid | Purity: 98% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1 L
Medchemexpress LLC Slb1122168 formic | 2999629-17-1 | 99.9% | 403.56 | C23H37N3O3 | 10 MG
SLB1122168 formic is a research-stage small molecule that inhibits Spns2-mediated sphingosine-1-phosphate (S1P) release. It has reported in vitro potency and is supplied for laboratory research with recommended storage and handling per the Safety Data Sheet.
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 1 ML
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
- Potent PKCiota inhibitor with an IC50 of 2.8 nM.
- Also inhibits PKC-α with an IC50 of 71 nM.
- Inhibits PKC-ε with an IC50 of 350 nM.
Medchemexpress LLC CBI1 formic | 461.40 | 100 MG
CBI1 formic is a covalent BAX inhibitor that selectively derivatizes BAX at C126. It inhibits BAX activation triggered by ligands or point mutagenesis, blocking t-2-hex lipidation and oligomerization of BAX.
- Inhibits BAX activation induced by BH3 ligands
- Blocks t-2-hex lipidation and oligomerization
- For research use only
Medchemexpress LLC GZD856 formic | 2804039-78-7 | 95.4% | 578.58 g/mol | C30H29F3N6O3 | 1 ML
GZD856 formic is a research-grade small-molecule inhibitor supplied as a 10 mM solution in DMSO for laboratory use. It is provided as the formic salt in a 1 mL vial and is intended for in vitro and exploratory studies needing a pre-dissolved, characterized compound.
- Pre-formulated 10 mM solution for immediate use.
- Supplied in a 1 mL vial for small-scale experiments.
- Formic salt form to enhance solubility and stability.
- Purity determined by HPLC, reported at 95.36%.
- Molecular weight 578.58 g/mol; formula C30H29F3N6O3.